Publications

Preprints

Peer-reviewed journal articles

Fukuzawa A., Koch D., Grover S., Rees M., Gautel M. (2021) When is an obscurin variant pathogenic? The impact of Arg4344Gln and Arg4444Trp variants on protein–protein interactions and protein stability. Forthcoming in: Human Molecular Genetics.

Koch D. (2020): Homo-Oligomerisation in Signal Transduction: Dynamics, Homeostasis, Ultrasensitivity, Bistability. In: Journal of Theoretical Biology, 499: 110305.

Gebharter A., Koch D. (2018): Combining causal Bayes nets and cellular automata: A hybrid modeling approach to mechanisms. Forthcoming in: The British Journal for the Philosophy of Science

Ali I.,  Eu S., Koch D., Bleimling N., Goody R.S., Müller, M.P. (2018): Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae. In: Acta Crystallographica Section F Structural Biology Communications, 74(5): 315-321.

Koch D., Eisinger R.S., Gebharter A. (2017): A causal Bayesian network model of disease progression mechanisms in chronic myeloid leukemia. In: Journal of Theoretical Biology, 433: 94-105.

Koch D., Rai A., Ali I., Bleimling B., Friese T., Brockmeyer A., Janning P., Goud B. Itzen A., Müller M.P., Goody R.S. (2016): A pull-down procedure for the identification of unknown GEFs for small GTPases. In: Small GTPases, 7(2):93-106.

Koch D. (2015): It’s Not (Only) The Joke’s Fault: A Speech Act Approach To Offensive Humor. In: Philosophisches Jahrbuch, 122(2): 318-338.

Wiegandt D., Vieweg S., Hofmann F., Koch D., Li F., Wu Y., Itzen A., Müller M.P., Goody R.S. (2015): Locking GTPases covalently in their functional states. In: Nature communications, 6: 7773.